Actinic

"Eczema" or dermatitis is the name given to an inflammatory process of the skin. Itching, scaling, blistering, weeping, scabbing, thickening of the skin surface, and scratch marks characterize this skin condition.

Over thirty skin diseases feature eczema. For example:

  • atopic dermatitis
  • nummular or coin shaped eczema
  • lichen simplex chronicus
  • dermatitis of the eyelids
  • scalp dermatitis
  • dyshidrotic eczema or "palm and sole eczema" irritant & allergic dermatitis due to exposure to a substance to which the skin reacts
  • even some nutritional or hereditary disorders

Atopic Dermatitis

The most common of the diseases characterized by eczema is called "Atopic (meaning out of place) Dermatitis."

It occurs in association with a personal or family history of hay fever, asthma, allergic rhinitis, or atopic dermatitis.

It affects about 15% to 20% of the world's population.

It can cause significant disruption in the quality of life. Itching associated with eczema is considered by most as more disturbing than pain. It impedes concentration on work or study, and it can strain relationships. When it affects sleep, it can cause irritability and exhaustion.

Atopic dermatitis at an early age presents with scaly, red patches on the face and neck, the scalp, the arms and legs and on the back of the hands. Later, the lesions are seen on the folds of the neck, the front of the elbows and behind the knees. Sometimes the eczema favors the palms and soles causing tiny blisters that evolve into scabbing and fissuring that bleeds easily.

For more information about Atopic Dermatitis, please visit: www.dermnet.org.nz/dna.atopic.dermatitis/info.html

 
Appearance of atopic dermatitis:
  • Very dry skin.
  • Often red and scaly with a rough, sandpaper-like texture that can resemble fish or crocodile skin.
  • It may resemble a fungus infection with whitish spots on the arms, a condition called pityriasis alba.
How is Eczema or Atopic Dermatitis Diagnosed?

The diagnosis is often easy to make by the trained eye of the dermatologist, but sometimes a biopsy or microscopic exam of a tiny piece of the affected skin is needed. Some laboratory tests like a blood cell count may show a type of white cell, called eosinophil, in higher than normal amounts. In addition, the level of a protein called IgE may be significantly elevated in the blood.

What Triggers Eczema?

To find the cause for some eczemas, the dermatologist usually depends on the medical history: i.e., the patient is asked to recall those factors such as stress, climate, dust, animals, foods, etc., that may trigger flares of dermatitis or at least cause itching. If the history is not clear, allergy tests may be needed. Tests may be in the form of patch tests, under which perfumes, preservatives, topical antibiotics, metals like nickel, etc., are placed under patches on the skin. These are left covered for two (2) days to see if a reaction is obtained. If so, the substance at the reaction site becomes a suspect in the cause of the eczema. Other allergy tests done by allergists, primarily to determine an airborne, environmental, animal, or food allergy, may be performed by pricking the skin with a needle and observing if a drop of one of the usual culprits, i.e., dust mites, cat dander or peanuts, caused a reaction. Less often, a blood test may be used to look for the trigger of the eczema.

What Are the Treatment Options for Eczema?

Diet
We advise the patient on the ways to eliminate possible triggers. A diet eliminating peanuts, milk, eggs and other foodstuffs, is sometimes suggested.

Breastfeeding for Infants
Breastfeeding may be recommended for infants of parents who have eczema, asthma, hay fever or hives.

Skin Care Regimens
Proper skin care and hygiene such as the use of gentle cleansers and tepid instead of hot water are also recommended. We often rely on a variety of ointments, creams and lotions to alleviate itch and suppress skin inflammation. Environmental control by means of regulating room temperature and humidity, vacuuming to reduce dust and animal dander can be helpful.

Topical Steroids
Until recently, topical steroids were the most often prescribed medications for eczema. However, chronic use of these steroids causes thinning of the skin which can lead to bruising, stretch marks, and infections. When overused, these medications can be absorbed and cause systemic effects.

Topical immuno-modulators
Fortunately, a new class of topical medication called "topical immuno-modulators" was introduced in 2001. These ointments and creams are as effective as some of the most powerful steroids, yet they have only minor risks such as transient stinging when first applied. The ointments and creams are not absorbed and do not thin the skin.

We do not recommend unproven topical agents like herbal medications in our practice as they are unregulated and some have been found to have toxic side effects causing liver and kidney toxicity or can contain steroids not mentioned on their labels.

Ultraviolet Light
Some forms of ultraviolet light are useful in reducing itching, thus breaking the itch - scratch cycle that perpetuates many eczemas. At our office, we mainly use a type of new ultraviolet light called Narrowband UVB, which is extremely helpful. UVA light may also be prescribed with a pill called psoralen ("PUVA treatment"). We do not recommend that our patients go to tanning salons.
Oral Medications

Antihistamines
Both 1st and 2nd generation antihistamines may be considered to alleviate itching. First generation antihistamines, like Benedryl® are safe, but can be sedating. Second generation antihistamines, which do not cross the blood brain barrier, are non-sedating.

Cortisone
Short courses (5 to 20 days) of oral steroids like prednisone, or intramuscular steroid injections, may be very helpful and safe for some patients who do not have diabetes, high blood pressure, stomach or duodenal ulcers, or glaucoma. Long courses should be avoided. Rarely will patients be allowed to have prednisone or intramuscular steroid injections more than 3 to 4 times a year.

Immunosuppressive drugs
Immunosuppressive drugs like Azathioprine best known as Imuran® or Mycophenolate Mofetil, known as Cell-Cept®, and Cyclosporine, known as Neoral®, or Gengraf® can be very helpful. However, they require careful monitoring by our physicians.

Interferon Injections
Interferon shots may be helpful in some severe cases.

Eczema Research
The doctors at Texas Dermatology Associates have participated and currently partake in many research studies and clinical trials for new treatments for eczema and atopic dermatitis. In this way, we have developed significant expertise on the subject. Our physicians lecture extensively and participate on advisory boards for pharmaceutical companies, both in the United States and abroad.

For more information about Eczema, please visit: www.eczema-assn.org

2008 © Copyright, Texas Dermatology Associates, P.A.

SparkLogo